4-Trifluoromethyl-1,2-phenylenediamine → HCID 11570465, compound

HRID 730247Notes

Reaction equation

HRID 730247 reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:4]=[C:5]([NH2:10])[C:6]([NH2:9])=[CH:7][CH:8]=1.[S:13]1[C:17]([S:18](Cl)(=[O:20])=[O:19])=[CH:16][C:15]2[CH:22]=[CH:23][CH:24]=[CH:25][C:14]1=2>>[F:1][C:2]([F:11])([F:12])[C:3]1[CH:8]=[CH:7][C:6]([NH:9][S:18]([C:17]2[S:13][C:14]3[CH:25]=[CH:24][CH:23]=[CH:22][C:15]=3[CH:16]=2)(=[O:20])=[O:19])=[C:5]([NH:10][S:18]([C:17]2[S:13][C:14]3[CH:25]=[CH:24][CH:23]=[CH:22][C:15]=3[CH:16]=2)(=[O:19])=[O:20])[CH:4]=1

Participants

3

Reactant 2

HCID 5208224-Trifluoromethyl-1,2-phenylenediamineHCID 27763331-Benzothiophene-2-sulfonyl chloride

Product 1

HCID 11570465HCID 11570465, compoundYield 53.3%

Procedure

N,N′-(4-Trifluoromethyl-1,2-phenylene)bis(1-benzothiophene-2-sulfonamide) (100 mg) was prepared by using 4-trifluoromethyl-benzene-1,2-diamine (0.06 g, 0.33 mmol) and benzo[b]thiophene-2-sulfonyl chloride (0.157 g, 0.67 mmol), following procedure as in Example 32.

Sources & evidence

ORD record
ord-6e7d5da2332e49b2b68abfbd976b39bc
Source dataset
uspto-grants-2009_09
Patent number
US07582673B2

Reaction notes

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