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HRID730279

反应详情

EQUATION

反应方程式

HRID 730279 的结构方程式

REACTANTS

反应物

2
结构：Nc1ccc2cc[nH]c2c1
HCID256096

6-Aminoindole

C8H8N2

结构：Cc1nc(C(C)(C)C)ccc1/C=C/C(=O)O
HCID57808155

(2E)-3-[6-(1,1-Dimethylethyl)-2-methyl-3-pyridinyl]-2-propenoic acid

C13H17NO2

PRODUCTS

生成物

1
结构：Cc1nc(C(C)(C)C)ccc1/C=C/C(=O)Nc1ccc2cc[nH]c2c1
HCID10286636

未命名化合物

PROCEDURE

实验过程

Analogous to the procedure used to prepare Example 1, (2E)-3-[6-(tert-butyl)-2-methyl(3-pyridyl)]prop-2-enoic acid, Example 75(c), (220 mg, 1.0 mmol) and 6-aminoindole (130 mg, 1.0 mmol, Lancaster) provided, after purification by silica gel chromatography (55:45 hexane:EtOAc), the title compound as a yellow solid. MP 182° C. MS (ESI, pos. ion) m/z: 334 (M+1).

WORKUP

后处理

  1. customprovided
  2. customafter purification by silica gel chromatography (55:45 hexane:EtOAc)