Hydrochloric Acid → HCID 68816706, compound

Participants

Reaction Steps

[2-(1-Benzyl-3-methyl-2-oxo-2,3-dihydro-1H-benzoimidazol-4-yloxy)-ethyl]-methyl-carbamic acid tert-butyl ester (92 mg, 0.223 mmol) was dissolved in 1 mL ethanol and combined with 0.5 mL of 2N ethanolic HCl, and the resulting solution was refluxed 30 minutes. On cooling, a white precipitate was observed. The solid was filtered and dried for 18 hours under vacuum to give 47 mg of 1-benzyl-3-methyl-4-(2-methylamino-ethoxy)-1,3-dihydro-benzoimidazol-2-one hydrochloride. MP: 203.8-205.1° C. MS: 312 (M+H)+.

Provenance & Evidence