反应详情

A suspension of 0.57 g (1.85 mmol) 1-benzyl-4-(1,1-dioxo-hexahydro-1λ6-thiopyran-4-yl)-piperazine and 300 mg 10% Pd/C in 30 mL MeOH was hydrogenated at 50° C. and 50 psi hydrogen pressure for 10 h. The catalyst was removed by suction filtering and the filtrate was concentrated by evaporation i. vac. The product was reacted further without purification.

1. customwas hydrogenated at 50° C.
2. customThe catalyst was removed by suction
3. filtrationfiltering
4. concentrationthe filtrate was concentrated by evaporation i
5. customThe product was reacted further without purification