3,5-Dichloro-2-fluoropyridine → HCID 66837860, compound

HRID 73065Notes

Reaction equation

HRID 73065 reaction equation
[Cl:1][C:2]1[C:3](F)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[O:10]1[C:14]2[CH:15]=[CH:16][C:17]([CH2:19][NH:20][S:21]([C:24]3[CH:33]=[CH:32][C:27]([C:28]([O:30][CH3:31])=[O:29])=[CH:26][CH:25]=3)(=[O:23])=[O:22])=[CH:18][C:13]=2[CH:12]=[CH:11]1>>[O:10]1[C:14]2[CH:15]=[CH:16][C:17]([CH2:19][N:20]([C:3]3[C:2]([Cl:1])=[CH:7][C:6]([Cl:8])=[CH:5][N:4]=3)[S:21]([C:24]3[CH:33]=[CH:32][C:27]([C:28]([O:30][CH3:31])=[O:29])=[CH:26][CH:25]=3)(=[O:23])=[O:22])=[CH:18][C:13]=2[CH:12]=[CH:11]1

Participants

3

Reactant 2

HCID 27832563,5-Dichloro-2-fluoropyridineHCID 66837840Methyl 4-(N-(benzofuran-5-ylmethyl)sulfamoyl)benzoate

Product 1

HCID 66837860HCID 66837860, compound

Procedure

The titled compound was prepared according to the procedure described in step-2 of Example 1 from 3,5-dichloro-2-fluoropyridine and methyl 4-(N-(benzofuran-5-ylmethyl)sulfamoyl)benzoate (step-1 of Example 1).

Sources & evidence

ORD record
ord-0bd93241caa349369a1d183fe6d446f4
Source dataset
uspto-grants-2014_09
Patent number
US08829026B2

Reaction notes

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