HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → Tert-butyl 4-(3-chloropyridin-4-yl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | 3,4-Dichloropyridine | HCID 2736081 | — |
| Product | Tert-butyl 4-(3-chloropyridin-4-yl)piperazine-1-carboxylate | HCID 11558451 | — |
Reaction Steps
The pyridine from step (a) above (5 g, 3.38 mmol) and tert-butylpiperazinecarboxylate (6.29 g, 3.38 mmol, Aldrich) reacted under the conditions of Example 3a to give the title compound as an orange oil. MS (ESI, pos. ion) m/z: 298 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-732268ec5a8647c29b9c681af7cf45ba |
| Source note | uspto-grants-2009_09 |