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HRID 730723생성일: 2026년 10월 25일

1-(3,5-Dichloropyridin-4-yl)piperazine → 6-tert-Butyl-2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-1H-benzoimidazole

https://huagongshe.com/reaction/730723

반응식

참여 물질

역할이름HCID투입량
반응물1-(3,5-Dichloropyridin-4-yl)piperazineHCID 2799984—
반응물6-tert-Butyl-2-chloro-1H-benzoimidazoleHCID 11586517—
생성물6-tert-Butyl-2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-1H-benzoimidazoleHCID 57835077—

반응 단계

The 6-tert-butyl-2-chloro-1H-benzoimidazole (209 mg, 1 mmol, Example 17b) and 1-(3,5-dichloropyridin-4-yl)piperazine (464 mg, 2 mmol, Maybridge) reacted under the conditions of Example 1d to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 404 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07582761B2
출처 데이터셋uspto-grants-2009_09
ORD IDord-bd8da0e3de11476497b87fa16811cafd
출처 메모uspto-grants-2009_09