HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → 4-Nitro-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 1,2-Benzenediamine, 3-nitro-5-(trifluoromethyl)- | HCID 5066063 | — |
| Product | 4-Nitro-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one | HCID 11630155 | — |
Reaction Steps
The reaction of 3-nitro-5-(trifluoromethyl)benzene-1,2-diamine (2.2 g, 10 mmol) with 1,1′-carbonyldiimidazole (1.78 g, 11 mmol, Aldrich) under the conditions of Example 1b afforded the title compound as a yellow solid. MS (ESI, pos. ion) m/z: 248 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-a945950ee2b24cd7beae1665faf102fc |
| Source note | uspto-grants-2009_09 |