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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730783Generated: October 29, 2026

(5-Chloro-6-(piperazin-1-yl)pyridin-3-yl)methanol → HCID 178519826, compound

https://huagongshe.com/reaction/730783

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Chloro-6-(piperazin-1-yl)pyridin-3-yl)methanolHCID 11514124—
Reactant4-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazoleHCID 11594585—
ProductHCID 178519826HCID 178519826—

Reaction Steps

4-Bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole (180 mg, 0.6 mmol, Example 6b) reacted with (5-chloro-6-piperazin-1-yl-pyridin-3-yl)methanol (228 mg, 1 mmol, Example 60a) under. the conditions of Example 3c to give the title compound as a white solid. MS (ESI, pos. ion) m/z: 490 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582761B2
Source datasetuspto-grants-2009_09
ORD IDord-78458b2a1c904323b48a0431543840d8
Source noteuspto-grants-2009_09