HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole → HCID 178461527, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole | HCID 11638867 | — |
| Reactant | (R)-1-(3-chloropyridin-2-yl)-3-methylpiperazine | HCID 11658551 | — |
| Product | HCID 178461527 | HCID 178461527 | — |
Reaction Steps
The piperazine from step (a) above (84 mg. 0.4 mmol) reacted with 2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole (105 mg, 0.3 mmol, Example 51b) under the conditions of Example 3c to give the title compound as a white amorphous solid. MS (ESI, pos. ion) m/z: 526 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7637c84f2aeb472798cdb0e58f8cfad0 |
| Source note | uspto-grants-2009_09 |