HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-6-(trifluoromethyl)-1H-benzimidazole → HCID 10475814, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-6-(trifluoromethyl)-1H-benzimidazole | HCID 337905 | — |
| Reactant | 4-(3-chlorophenyl)piperidin-4-ol | HCID 10013391 | — |
| Product | HCID 10475814 | HCID 10475814 | — |
Reaction Steps
4-(3-Chloro-phenyl)-piperidin-4-ol (0.25 g, 1.18 mmol, Aldrich) reacted with 2-chloro-6-trifluoromethyl-1H-benzoimidazole (0.26 g, 1.18 mmol, Example 1c) under the conditions of Example 94d to give the title compound as a white solid. M.p. 246.7-247.4° C. MS (ESI, pos. ion) m/z: 424 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7f776caccc744c4ebd95c305014cc756 |
| Source note | uspto-grants-2009_09 |