HuagongsheHuagongshe Chemistry Print Report · For research reference only
{5-Chloro-6-[(3R)-3-methylpiperazin-1-yl]pyridin-3-yl}methanol → HCID 178461535, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {5-Chloro-6-[(3R)-3-methylpiperazin-1-yl]pyridin-3-yl}methanol | HCID 11550484 | — |
| Reactant | HCID 178506061 | HCID 178506061 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178461535 | HCID 178461535 | — |
Reaction Steps
A mixture of 7-bromo-2-chloro-5-trifluoromethyl-1H-benzoimidazole (96 mg, 0.32 mmol, Example 6b) and {5-chloro-6-[(3R)-3-methyl-piperazin-1-yl]-pyridin-3-yl}-methanol (96 mg, 0.4 mmol, Example 150a) in dioxane (2 mL) reacted under the conditions of Example 3c to give the title compound. MS (ESI, pos. ion) m/z: 506 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-4368e09153444375a8018542017de7bf |
| Source note | uspto-grants-2009_09 |