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HRID730876

反应详情

EQUATION

反应方程式

HRID 730876 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1CNCCN1
HCID7330434

2-Methylpiperazine, (R)-

C5H12N2

结构：CC(C)(O)c1cnc(Cl)c(Cl)c1
HCID77230300

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H]1CN(c2ncc(C(C)(C)O)cc2Cl)CCN1
HCID67400439

5-Chloro-α,α-dimethyl-6-[(3R)-3-methyl-1-piperazinyl]-3-pyridinemethanol

C13H20ClN3O

PROCEDURE

实验过程

A mixture of 2-(5,6-dichloro-pyridin-3-yl)-propan-2-ol from step (b) above (140 mg, 0.68 mmol) and (R)-(−)-2-methyl-piperazine (75 mg, 0.75 mmol, Aldrich) reacted under the conditions of Example 3a to give the title compound. MS (ESI, pos. ion) m/z: 270 (M+1).

WORKUP

后处理

  1. customreacted under the conditions of Example 3a