HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,4-Trifluorobenzeneboronic acid → HCID 178461532, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,4-Trifluorobenzeneboronic acid | HCID 2783280 | — |
| Reactant | 4-bromo-2-[(2R)-4-(3,5-dichloro-pyridin-2-yl)-2-methyl-piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole | HCID 57835191 | — |
| Product | HCID 178461532 | HCID 178461532 | — |
Reaction Steps
4-Bromo-2-[(2R)-4-(3,5-dichloro-pyridin-2-yl)-2-methyl-piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole (204 mg, 0.4 mmol, Example 149b) and 4,5,6-trifluorophenylboronic acid (141 mg, 0.8 mmol, Aldrich) reacted under the conditions of Example 158 to give the title compound. MS (ESI, pos. ion) m/z: 504 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-8fe87e3e609b4dff932e28c5c92799a8 |
| Source note | uspto-grants-2009_09 |