HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzoic Acid → HCID 178461547, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzoic Acid | HCID 6318 | — |
| Reactant | HCID 178461542 | HCID 178461542 | — |
| Product | HCID 178461547 | HCID 178461547 | — |
Reaction Steps
{6-[(3R)-4-(7-Amino-5-trifluoromethyl-1H-benzoimidazol-2-yl)-3-methyl-piperazin-1-yl]-5-chloro-pyridin-3-yl}-methanol (221 mg, 0.5 mmol, Example 175b) and 4-chloro-benzoic acid (86 mg, 0.55 mmol, Aldrich) reacted under the conditions of Example 65 to give the title compound as a white solid. MS (ESI, pos. ion) m/e: 579 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582761B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-37387eafdab2461bb4aa05b9754f64e4 |
| Source note | uspto-grants-2009_09 |