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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730896Generated: October 29, 2026

4-Chlorobenzoic Acid → HCID 178461547, compound

https://huagongshe.com/reaction/730896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzoic AcidHCID 6318—
ReactantHCID 178461542HCID 178461542—
ProductHCID 178461547HCID 178461547—

Reaction Steps

{6-[(3R)-4-(7-Amino-5-trifluoromethyl-1H-benzoimidazol-2-yl)-3-methyl-piperazin-1-yl]-5-chloro-pyridin-3-yl}-methanol (221 mg, 0.5 mmol, Example 175b) and 4-chloro-benzoic acid (86 mg, 0.55 mmol, Aldrich) reacted under the conditions of Example 65 to give the title compound as a white solid. MS (ESI, pos. ion) m/e: 579 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582761B2
Source datasetuspto-grants-2009_09
ORD IDord-37387eafdab2461bb4aa05b9754f64e4
Source noteuspto-grants-2009_09