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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730932Generated: November 1, 2026

HCID 57436583, compound → HCID 57436582, compound

https://huagongshe.com/reaction/730932

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57436583HCID 57436583—
CatalystPalladiumHCID 23938—
SolventMeOH tetrahydrofuranHCID 21899815—
ProductHCID 57436582HCID 5743658296%

Reaction Steps

2-(3-(N-Isopropylamino)methylphenyl)-4-nitroanisole (120 mg, 0.39 mmol) was dissolved in MeOH/THF (5 mL:5 mL), and 10% Pd/C (20 mg) was added. The slurry was stirred at room temperature under an atmosphere of H2 for 16 h. The slurry was then filtered and evaporated to afford 3-[3-(N-isopropylamino)methylphenyl]-4-methoxyaniline as a brown oil (101 mg, 0.37 mmol, 96%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582765B2
Source datasetuspto-grants-2009_09
ORD IDord-76026ac7943043c28474aac7b1f749ad
Source noteuspto-grants-2009_09