HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57436583, compound → HCID 57436582, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57436583 | HCID 57436583 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 57436582 | HCID 57436582 | 96% |
Reaction Steps
2-(3-(N-Isopropylamino)methylphenyl)-4-nitroanisole (120 mg, 0.39 mmol) was dissolved in MeOH/THF (5 mL:5 mL), and 10% Pd/C (20 mg) was added. The slurry was stirred at room temperature under an atmosphere of H2 for 16 h. The slurry was then filtered and evaporated to afford 3-[3-(N-isopropylamino)methylphenyl]-4-methoxyaniline as a brown oil (101 mg, 0.37 mmol, 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582765B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-76026ac7943043c28474aac7b1f749ad |
| Source note | uspto-grants-2009_09 |