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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 73098Generated: October 29, 2026

2,3-Dichloro-5-(trifluoromethyl)pyridine → Methyl 4-(N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((1-(2-hydroxy-2-methylpropyl)-1H-indazol-5-yl)methyl)sulfamoyl)benzoate

https://huagongshe.com/reaction/73098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dichloro-5-(trifluoromethyl)pyridineHCID 112234—
ReactantMethyl 4-(N-((1-(2-hydroxy-2-methylpropyl)-1H-indazol-5-yl)methyl)sulfamoyl)benzoateHCID 66837918—
ProductMethyl 4-(N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((1-(2-hydroxy-2-methylpropyl)-1H-indazol-5-yl)methyl)sulfamoyl)benzoateHCID 66837869—

Reaction Steps

The titled compound was prepared according to the procedure described in step-2 of Example 1 from 2,3-dichloro-5-(trifluoromethyl)pyridine and methyl 4-(N-((1-(2-hydroxy-2-methylpropyl)-1H-indazol-5-yl)methyl)sulfamoyl)benzoate (step-3 of Example 22).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829026B2
Source datasetuspto-grants-2014_09
ORD IDord-1fe8104008174f2dbdbb63ac78d32cff
Source noteuspto-grants-2014_09