2,3-Dichloro-5-(trifluoromethyl)pyridine → HCID 66837899, compound

HRID 73102Notes

Reaction equation

HRID 73102 reaction equation
Cl[C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=1.[Cl:13][C:14]1[CH:15]=[C:16]([CH:21]=[CH:22][C:23]=1[S:24](=[O:38])(=[O:37])[NH:25][CH2:26][C:27]1[CH:28]=[C:29]2[C:33](=[CH:34][CH:35]=1)[N:32]([CH3:36])[N:31]=[CH:30]2)[C:17]([O:19][CH3:20])=[O:18]>>[Cl:13][C:14]1[CH:15]=[C:16]([CH:21]=[CH:22][C:23]=1[S:24](=[O:37])(=[O:38])[N:25]([C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=1)[CH2:26][C:27]1[CH:28]=[C:29]2[C:33](=[CH:34][CH:35]=1)[N:32]([CH3:36])[N:31]=[CH:30]2)[C:17]([O:19][CH3:20])=[O:18]

Participants

3

Reactant 2

HCID 1122342,3-Dichloro-5-(trifluoromethyl)pyridineHCID 66837883methyl 3-chloro-4-(N-((1-methyl-1H-indazol-5-yl)methyl)sulfamoyl)benzoate

Product 1

HCID 66837899HCID 66837899, compound

Procedure

The titled compound was prepared according to the procedure described in step-2 of Example 1 from 2,3-dichloro-5-(trifluoromethyl)pyridine and methyl 3-chloro-4-(N-((1-methyl-1H-indazol-5-yl)methyl)sulfamoyl)benzoate (step-2 of Example 24).

Sources & evidence

ORD record
ord-59e19559f76f4fe398c5185be43bb3ff
Source dataset
uspto-grants-2014_09
Patent number
US08829026B2

Reaction notes

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