Potassium Carbonate → HCID 68814513, compound

Participants

Reaction Steps

The desired product was prepared using a procedure similar to step 5 of example 3. Thus, 4-(1,3-dibenzyl-2-phenyl-1H-indol-5-yl)-phenol (0.542 g, 1.163 mmol) was reacted with K2CO3 (0.225 g, 1.628 mmol) and bromoacetonitrile (0.195 g, 1.628 mmol) in acetone (10 ml) to give the product (0.486 g, 0.963 mmol, 83%) as a viscous, yellow oil. 1H NMR (DMSO-d6) δ 4.08 (s, 2H), 5.19 (s, 2H), 5.36 (s, 2H), 6.89 (d, J=7.3 Hz, 2H), 7.10-7.24 (m, 10H), 7.37-7.51 (m, 7H), 7.57 (d, J=8.9 Hz, 2H), 7.63 (s, 1H); [ESI(+)], m/z 505 (M+H)+.

Provenance & Evidence