6-(Aminomethyl)quinoline → Methyl 4-(N-(quinolin-6-ylmethyl)sulfamoyl)benzoate

HRID 73125Notes

Reaction equation

HRID 73125 reaction equation
Cl[S:2]([C:5]1[CH:14]=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[CH:7][CH:6]=1)(=[O:4])=[O:3].[N:15]1[C:24]2[C:19](=[CH:20][C:21]([CH2:25][NH2:26])=[CH:22][CH:23]=2)[CH:18]=[CH:17][CH:16]=1>>[N:15]1[C:24]2[C:19](=[CH:20][C:21]([CH2:25][NH:26][S:2]([C:5]3[CH:14]=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[CH:7][CH:6]=3)(=[O:4])=[O:3])=[CH:22][CH:23]=2)[CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 15143846-(Aminomethyl)quinolineHCID 4738388Methyl 4-(Chlorosulfonyl)benzoate

Product 1

HCID 66837881Methyl 4-(N-(quinolin-6-ylmethyl)sulfamoyl)benzoate

Procedure

The titled compound was prepared according to the procedure described in step-1 of Example 1 from methyl 4-(chlorosulfonyl)benzoate and quinolin-6-ylmethanamine.

Sources & evidence

ORD record
ord-d89e42c43c114c02baa3d64a539fefae
Source dataset
uspto-grants-2014_09
Patent number
US08829026B2

Reaction notes

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