Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 731402Generated: October 25, 2026

Acetal → 1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-(4-methyl-cyclohexyl)-3-(5-methyl-thiazol-2-yl)-urea

https://huagongshe.com/reaction/731402

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetalHCID 7765—
Reactant4-MethylcyclohexylamineHCID 80604—
Reactant2-Amino-5-methylthiazoleHCID 351770—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Product1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-(4-methyl-cyclohexyl)-3-(5-methyl-thiazol-2-yl)-ureaHCID 57883925—

Reaction Steps

1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-(4-methyl-cyclohexyl)-3-(5-methyl-thiazol-2-yl)-urea was prepared in an similar manner to example 2 according to general procedures (A) and (B) using 1,4-dioxaspiro[4.5]decan-8-one, 4-methylcyclohexylamine and 2-amino-5-methylthiazole. The acetale was then hydrolysed in the following way:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582769B2
Source datasetuspto-grants-2009_09
ORD IDord-e43b8a0352204a75bf3fdfcbe0c0c2b5
Source noteuspto-grants-2009_09