HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine → HCID 57688243, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | Dimethylsulphamoyl chloride | HCID 83372 | — |
| Reactant | tert-Butyl 2-oxopiperidine-1-carboxylate | HCID 7577838 | — |
| Reactant | HCID 86630188 | HCID 86630188 | — |
| Product | HCID 57688243 | HCID 57688243 | — |
Reaction Steps
{2-[3-Cyclohexyl-3-piperidin-4-yl-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester was pre-pared in a similar manner to the synthesis of example 12 from N-Boc piperidone, cyclo-hexylamine and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl, Boc deprotection, reaction with dimethylsulfamoyl chloride and hydrolysis of the ester moiety as described in general procedure (I) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582769B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-63b41943e9f147ab82a5c2a46c989920 |
| Source note | uspto-grants-2009_09 |