N-{2-[(Dicyclohexylcarbamoyl)amino]-1,3-thiazole-5-sulfonyl}glycine → {2-[3-(1-Acetyl-piperidin-4-yl)-3-cyclohexyl-ureido]-thiazole-5-sulfonylamino}-acetic acid

Participants

Role	Name	HCID	Charge
Reactant	N-{2-[(Dicyclohexylcarbamoyl)amino]-1,3-thiazole-5-sulfonyl}glycine	HCID 57688273	—
Reactant	N,N-Dicyclopentyl-N'-1,3-thiazol-2-ylurea	HCID 57688319	—
Reactant	(2-Amino-thiazole-5-sulfonylamino)acetic acid ethyl ester	HCID 86253773	—
Product	{2-[3-(1-Acetyl-piperidin-4-yl)-3-cyclohexyl-ureido]-thiazole-5-sulfonylamino}-acetic acid	HCID 57688275	—

Reaction Steps

Prepared in a similar manner to [2-(3,3-dicyclohexyl-ureido)-thiazole-5-sulfonylamino]-acetic acid via 1-(4-cyclohexylamino-piperidin-1-yl)-ethanone (General procedure 1) and (2-amino-thiazole-5-sulfonylamino)-acetic acid ethyl ester to give the title compound.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07582769B2
Source dataset	uspto-grants-2009_09
ORD ID	ord-ab47f8cfa7f043ed9baa90bb413f820f
Source note	uspto-grants-2009_09