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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 731463Generated: October 30, 2026

N-(4-Phenylcyclohexyl)cycloheptanamine → 2-{2-[3-Cycloheptyl-3-(4-phenyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2-methyl-propionic acid

https://huagongshe.com/reaction/731463

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-Phenylcyclohexyl)cycloheptanamineHCID 29770255—
ReactantEthyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoateHCID 57481427—
ReactantHCID 178455810HCID 178455810—
Product2-{2-[3-Cycloheptyl-3-(4-phenyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2-methyl-propionic acidHCID 57688358—

Reaction Steps

Prepared in a similar manner to {2-[3-cyclopentyl-3-(trans-4-ethyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid (via cycloheptyl-(4-phenyl-cyclohexyl)-amine and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582769B2
Source datasetuspto-grants-2009_09
ORD IDord-dbf8fb3d530243c5ac1d2e68d2048054
Source noteuspto-grants-2009_09