HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromopropane → HCID 178459273, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromopropane | HCID 7840 | — |
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | N-{2-[(Dicyclohexylcarbamoyl)amino]-1,3-thiazole-5-sulfonyl}glycine | HCID 57688273 | — |
| Reactant | 2-(2-Amino-thiazole-5-sulfonylamino)-2-methyl-propionic acid methyl ester | HCID 86630196 | — |
| Reactant | HCID 178459265 | HCID 178459265 | — |
| Reactant | HCID 178496618 | HCID 178496618 | — |
| Reactant | HCID 178518244 | HCID 178518244 | — |
| Product | HCID 178459273 | HCID 178459273 | — |
Reaction Steps
Prepared in a similar manner to [2-(3,3-dicyclohexyl-ureido)-thiazole-5-sulfonylamino]-acetic acid via cyclohexyl-(trans-4-propoxy-cyclohexyl)-amine (prepared according to the procedure described for the synthesis of {2-[3-cyclopentyl-3-(trans-4-methoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid (Step 1) using (trans-4-hydroxy-cyclohexyl)-isoindole-1,3-dione, 1-bromopropane and cyclohexanone) and 2-(2-amino-thiazole-5-sulfonylamino)-2-methyl-propionic acid methyl ester to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582769B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-475b6146efc240dfb45314e6b8052f4a |
| Source note | uspto-grants-2009_09 |