Isopropylamine → HCID 178457899, compound

HRID 731494Notes

Reaction equation

HRID 731494 reaction equation
[CH:1]1([N:7]([C@H]2CC[C@H](C)CC2)C(=O)NC2SC(S(N(C)CC(N(CC)CC)=O)(=O)=O)=CN=2)[CH2:6]CCC[CH2:2]1.[CH:36]1([N:42]([C@H:59]2[CH2:64][CH2:63][C@H:62](C)[CH2:61][CH2:60]2)[C:43](=[O:58])[NH:44][C:45]2[S:46][C:47]([S:50]([NH:53][CH2:54][C:55]([OH:57])=O)(=[O:52])=[O:51])=[CH:48][N:49]=2)[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]1.[CH:66](N)(C)C>>[CH:36]1([N:42]([C@H:59]2[CH2:60][CH2:61][C@H:62]([CH3:66])[CH2:63][CH2:64]2)[C:43](=[O:58])[NH:44][C:45]2[S:46][C:47]([S:50]([NH:53][CH2:54][C:55]([NH:7][CH:1]([CH3:6])[CH3:2])=[O:57])(=[O:51])=[O:52])=[CH:48][N:49]=2)[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]1

Participants

4

Reactant 3

HCID 6363IsopropylamineHCID 178461397HCID 178461397, compoundHCID 178464221HCID 178464221, compound

Product 1

HCID 178457899HCID 178457899, compound

Procedure

The title compound was prepared in a similar manner to 2-({2-[3-cyclohexyl-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazole-5-sulfonyl}-methyl-amino)-N,N-diethyl-acetamide using {2-[3-cyclohexyl-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazole-5-sulfonylamino}-acetic acid and isopropylamine.

Sources & evidence

ORD record
ord-04295f0fb899464089e99a664ae6809c
Source dataset
uspto-grants-2009_09
Patent number
US07582769B2

Reaction notes

Loading…