HCID 67483387, compound → HCID 178484759, compound

HRID 731498Notes

Reaction equation

HRID 731498 reaction equation
[CH:1]1([N:7]([C@H:24]2[CH2:29][CH2:28][C@H:27]([CH3:30])[CH2:26][CH2:25]2)[C:8](=[O:23])[NH:9][C:10]2[S:14][C:13]([S:15]([NH:18][CH2:19][C:20]([OH:22])=[O:21])(=[O:17])=[O:16])=[N:12][N:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:31]1(N[C@H]2CC[C@H](C)CC2)CCCCC1.C(OC(=O)CN(S(C1SC(N)=NN=1)(=O)=O)C)C>>[CH:1]1([N:7]([C@H:24]2[CH2:29][CH2:28][C@H:27]([CH3:30])[CH2:26][CH2:25]2)[C:8](=[O:23])[NH:9][C:10]2[S:14][C:13]([S:15]([N:18]([CH2:19][C:20]([OH:22])=[O:21])[CH3:31])(=[O:17])=[O:16])=[N:12][N:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 67483387HCID 67483387, compoundHCID 178461295HCID 178461295, compoundHCID 178461398HCID 178461398, compound

Product 1

HCID 178484759HCID 178484759, compound

Procedure

Prepared in a similar manner to {5-[3-cyclohexyl-3-(trans-4-methyl-cyclohexyl)-ureido]-[1,3,4]thiadiazole-2-sulfonylamino}-acetic acid via cyclohexyl-(trans-4-methyl-cyclohexyl)-amine and [(5-amino-1,3,4-thiadiazole-2-sulfonyl)-methyl-amino]-acetic acid ethyl ester to give the title compound.

Sources & evidence

ORD record
ord-323294e289994a159b7f25dfbd5bb475
Source dataset
uspto-grants-2009_09
Patent number
US07582769B2

Reaction notes

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