Sulfuryl chloride → HCID 178486285, compound

HRID 731499Notes

Reaction equation

HRID 731499 reaction equation
[CH3:1][NH:2][S:3]([C:6]1[S:10][C:9]([NH:11][C:12]([N:14]([CH:22]2[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)[C@H:15]2[CH2:20][CH2:19][C@H:18]([CH3:21])[CH2:17][CH2:16]2)=[O:13])=[N:8][CH:7]=1)(=[O:5])=[O:4].[C:28](NC1SC(S(Cl)(=O)=O)=C(C)N=1)(=O)C.S(Cl)(Cl)(=O)=O>>[CH3:1][NH:2][S:3]([C:6]1[S:10][C:9]([NH:11][C:12]([N:14]([CH:22]2[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)[C@H:15]2[CH2:20][CH2:19][C@H:18]([CH3:21])[CH2:17][CH2:16]2)=[O:13])=[N:8][C:7]=1[CH3:28])(=[O:4])=[O:5]

Participants

4

Reactant 3

HCID 24648Sulfuryl chlorideHCID 969512-Acetamido-4-methylthiazole-5-sulfonyl chlorideHCID 178486280HCID 178486280, compound

Product 1

HCID 178486285HCID 178486285, compound

Procedure

The title compound was prepared in a similar manner to 2-[3-cyclohexyl-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazole-5-sulfonic acid methylamide using 2-acetylamino-4-methyl-thiazole-5-sulfonyl chloride as the sulfonyl chloride.

Sources & evidence

ORD record
ord-1d99f43b6cde45d4959c10e27bda3bac
Source dataset
uspto-grants-2009_09
Patent number
US07582769B2

Reaction notes

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