反应详情

At room temperature, 13.8 g of 1-mercapto-1-phenylethane is dissolved in 50 mL of butyryl chloride. The mixture is stirred at room temperature for 6 hours. It is then cooled down to 0° C. and the reaction is quenched by careful addition of 100 ml of dry methanol in small portions. The mixture is then washed with bicarbonate, dried over magnesium sulfate, filtered and concentrated to give the butyrated compound in 98% yield.

1. temperatureIt is then cooled down to 0° C.
2. customthe reaction is quenched by careful addition of 100 ml of dry methanol in small portions
3. washThe mixture is then washed with bicarbonate
4. dry with materialdried over magnesium sulfate
5. filtrationfiltered
6. concentrationconcentrated
7. customto give the butyrated compound in 98% yield