Hydrochloric Acid → HCID 59186628, compound

Participants

Reaction Steps

A solution of EXAMPLE 1D (20.54 g, 55.4 mmol) in dioxane (100 mL) was treated with 1N NaOH (100 mL, 100 mmol), stirred overnight, acidified with 1N HCl, extracted with ethyl acetate (3×), dried (MgSO4), and filtered. Concentration of the filtrate gave a residue that was purified by silica gel chromatography eluting with to provide the desired product (xx g, xx %). MS (ESI) m/e 344 (M+H)+.

Provenance & Evidence