Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenacyl bromide → [3-Amino-4-ethyl-5-(4-phenoxy-phenylamino)-thiophen-2-yl]-phenyl-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenacyl bromide | HCID 6259 | — |
| 반응물 | Propionitrile | HCID 7854 | — |
| 반응물 | Butyronitrile | HCID 8008 | — |
| 반응물 | Cyclopentyl isothiocyanate | HCID 141792 | — |
| 반응물 | 1-Isothiocyanato-4-phenoxybenzene | HCID 145694 | — |
| 반응물 | 5-(Bromoacetyl)-3-phenylisoxazole | HCID 2735532 | — |
| 생성물 | [3-Amino-4-ethyl-5-(4-phenoxy-phenylamino)-thiophen-2-yl]-phenyl-methanone | HCID 57837075 | — |
반응 단계
[3-Amino-4-ethyl-5-(4-phenoxy-phenylamino)-thiophen-2-yl]-phenyl-methanone was prepared as described in Example 43 substituting Propanenitrile, Isothiocyanato-cyclopentane and 2-Bromo-1-(3-phenyl-isoxazol-5-yl)-ethanone with butanenitrile, 4-phenoxyphenylisothiocyanate and 2-Bromo-1-phenyl-ethanone respectively to provide compound 1-243. MS(ESI) [M+H+]+=415.0
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07585859B2 |
| 출처 데이터셋 | uspto-grants-2009_09 |
| ORD ID | ord-b0c1c804a8b247e494884c24586d4bec |
| 출처 메모 | uspto-grants-2009_09 |