HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Ethylpyridin-2-amine → 7-Ethyl-2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Ethylpyridin-2-amine | HCID 118425 | — |
| Edukt | 4-(Bromoacetyl)-5-methyl-3-phenylisoxazole | HCID 2735531 | — |
| Produkt | 7-Ethyl-2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridine | HCID 24738343 | 27% |
Reaktionsschritte
As described for Example 2, 4-(bromoacetyl)-5-methyl-3-phenylisoxazole (commercially available) (140 mg, 0.5 mmol) was converted, using 2-amino-4-ethylpyridine instead of 2-amino-3-methylpyridine, to the title compound (33 mg, 27%) which was obtained as a yellow oil. MS: m/e=304.0 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07585874B2 |
| Quelldatensatz | uspto-grants-2009_09 |
| ORD ID | ord-f12fadb5605946658af42cfd595c3a96 |
| Quellennotiz | uspto-grants-2009_09 |