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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 731616Erstellt: 25. Oktober 2026

4-Ethylpyridin-2-amine → 7-Ethyl-2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridine

https://huagongshe.com/reaction/731616

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-Ethylpyridin-2-amineHCID 118425—
Edukt4-(Bromoacetyl)-5-methyl-3-phenylisoxazoleHCID 2735531—
Produkt7-Ethyl-2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridineHCID 2473834327%

Reaktionsschritte

As described for Example 2, 4-(bromoacetyl)-5-methyl-3-phenylisoxazole (commercially available) (140 mg, 0.5 mmol) was converted, using 2-amino-4-ethylpyridine instead of 2-amino-3-methylpyridine, to the title compound (33 mg, 27%) which was obtained as a yellow oil. MS: m/e=304.0 [M+H]+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07585874B2
Quelldatensatzuspto-grants-2009_09
ORD IDord-f12fadb5605946658af42cfd595c3a96
Quellennotizuspto-grants-2009_09