HCID 24738993, compound → HCID 86613884, compound

Participants

Reaction Steps

As described for Example 45, 6-bromo-2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridine (100 mg, 0.28 mmol) instead of 7-bromo-2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridine, was converted to 2-(5-methyl-3-phenyl-isoxazol-4-yl)-6-trimethylsilanylethynyl-imidazo[1,2-a]pyridine (39 mg, 37% MS: m/e=372.1 [M+H]+) and then to the title compound (19 mg, 69%) which was obtained as a light yellow foam. MS: m/e=300.3 [M+H]+.

Provenance & Evidence