HCID 69066028, compound → HCID 24739474, compound

Participants

Reaction Steps

As described for Example 46, 2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridine-6-carboxylic acid (1.62 g, 5.1 mmol) instead of 2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridine-7-carboxylic acid, was converted to [2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridin-6-yl]-carbamic acid tert-butyl ester (910 mg, 46% MS: m/e=389.5 [M+H]+) and then to the title compound (506 mg, 78%) which was obtained as a light grey foam. MS: m/e=291.0 [M−H]−.

Provenance & Evidence