HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 731888Generated: October 25, 2026
Water → 1-allyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
https://huagongshe.com/reaction/731888
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Allyl iodide | HCID 11166 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 178508705 | HCID 178508705 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-allyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | HCID 24905271 | — |
Reaction Steps
3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (50 mg, 0.21 mmol) was dissolved in DMF (1.5 mL) and K2CO3 (110 mg, 0.8 mmol) and allyl iodide (23 μL, 0.25 mmol) were added. The reaction was heated to 60° C. overnight, then cooled to RT and poured into water (30 mL). The precipitate was collected by filtration. ESI-MS (M+H)+ m/z calcd 302.1, found 302.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07585868B2 |
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| Source dataset | uspto-grants-2009_09 |
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| ORD ID | ord-b3c1c6933a5b43ed9a3b728e330ec142 |
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| Source note | uspto-grants-2009_09 |
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