HRID731911

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID81514

Butanoyl chloride, 3,3-dimethyl-

C6H11ClO

结构：Cc1cc(Nc2ncnc3cnc(F)cc23)ccc1OC1CCN(C(=O)C2CCCC2)CC1

HCID69051928

未命名化合物

结构：Cc1cc(Nc2ncnc3cnc(N4CCOCC4)cc23)ccc1OC1CCNCC1

HCID69057517

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(Nc2ncnc3cnc(N4CCOCC4)cc23)ccc1OC1CCN(C(=O)CC(C)(C)C)CC1

HCID44426279

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from [3-Methyl-4-(piperidin-4-yloxy)-phenyl]-(6-morpholin-4-yl-pyrido[3,4-d]pyrimidin-4-yl)-amine and tert-butylacetyl chloride by a procedure analogous to the synthesis of Cyclopentyl-{4-[4-(6-fluoro-pyrido[3,4-d]pyrimidin-4-ylamino)-2-methyl-phenoxy]-piperidin-1-y}-methanone above.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b4e86cc2b87845a594f85e1362645728
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07585869B2
来源说明: uspto-grants-2009_09

反应 SMILES

[CH3:1][C:2]1[CH:3]=[C:4]([NH:15][C:16]2[C:17]3[CH:25]=[C:24]([N:26]4[CH2:31][CH2:30][O:29][CH2:28][CH2:27]4)[N:23]=[CH:22][C:18]=3[N:19]=[CH:20][N:21]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1.[C:32]([CH2:36][C:37](Cl)=[O:38])([CH3:35])([CH3:34])[CH3:33].C1(C(N2CCC(OC3C=CC(NC4C5C=C(F)N=CC=5N=CN=4)=CC=3C)CC2)=O)CCCC1>>[CH3:33][C:32]([CH3:35])([CH3:34])[CH2:36][C:37]([N:12]1[CH2:13][CH2:14][CH:9]([O:8][C:7]2[CH:6]=[CH:5][C:4]([NH:15][C:16]3[C:17]4[CH:25]=[C:24]([N:26]5[CH2:31][CH2:30][O:29][CH2:28][CH2:27]5)[N:23]=[CH:22][C:18]=4[N:19]=[CH:20][N:21]=3)=[CH:3][C:2]=2[CH3:1])[CH2:10][CH2:11]1)=[O:38]