HCID 11241643, compound → 748808-04-0

HRID 731953Notes

Reaction equation

HRID 731953 reaction equation
[F:1][C:2]1([F:16])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([N+:11]([O-])=O)[CH:9]=2)[N:4]([CH3:14])[C:3]1=[O:15]>[Ni]>[NH2:11][C:8]1[CH:9]=[C:10]2[C:5](=[CH:6][CH:7]=1)[N:4]([CH3:14])[C:3](=[O:15])[C:2]2([F:16])[F:1]

Participants

3

Reactant 1

HCID 11241643HCID 11241643, compound

Product 1

HCID 11458271748808-04-0

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

3,3-Difluoro-1-methyl-5-nitro-1,3-dihydro-2H-indol-2-one was subjected to a hydrogenation reaction using a Raney-Ni catalyst under a hydrogen stream to obtain 5-amino-3,3-difluoro-1-methyl-1,3-dihydro-2H-indol-2-one.

Sources & evidence

ORD record
ord-4e6d134a8f8b46079666619f899f400d
Source dataset
uspto-grants-2009_09
Patent number
US07585878B2

Reaction notes

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