Thioglycolic Acid → HCID 23112226, compound

HRID 731957Notes

Reaction equation

[CH2:1]([N:3]([CH2:16][C:17]1[CH:22]=[C:21]([C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH:20]=[CH:19][C:18]=1[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)S(C1C=CC=CC=1[N+]([O-])=O)(=O)=O)[CH3:2].C(O)(=O)CS>>[CH2:1]([NH:3][CH2:16][C:17]1[CH:22]=[C:21]([C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH:20]=[CH:19][C:18]=1[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[CH3:2]

Participants

Reactant 2

HCID 1133Thioglycolic Acid

HCID 23112260HCID 23112260, compound

Product 1

HCID 23112226HCID 23112226, compound

Procedure

Ethyl 2-({ethyl[(2-nitrophenyl)sulfonyl]amino}methyl)biphenyl-4-carboxylate was treated with thioglycolic acid in the presence of a base to obtain ethyl 2-[(ethylamino)methyl]biphenyl-4-carboxylate.

Sources & evidence

ORD record: ord-0d1f3040a7484152b26dd70defd07d8a
Source dataset: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07585878B2

Reaction notes

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