m-Chloroperbenzoic acid → HCID 23143250, compound

Participants

Reaction Steps

A mixture of methyl 3-{4-[(4-{[[3-(methylthio)propyl](4-phenyl-1,3-thiazol-2-yl)amino]methyl}benzyl)oxy]phenyl}-propanoate (280 mg), m-chloroperbenzoic acid (122 mg) and tetrahydrofuran (10 mL) was stirred at room temperature for 3 hr. The reaction mixture was concentrated and the residue was purified by silica gel column chromatography (ethyl acetate:hexane=1:19-1:0 in volume ratio) to give the title compound (180 mg, yield 62%) as a yellow oil.

Provenance & Evidence