Hydrochloric Acid → HCID 68517807, compound

Participants

Reaction Steps

Dissolve the compound of Example 20 (196 mg, 0.34 mmol) in ethyl acetate (1 mL) and diethyl ether (9 mL). Add 2M HCl in diethyl ether (340 μl, 680 μmol) to the stirred solution. Allow the suspension to stir for 10 minutes. Filter the solids through a Buchner funnel. Dry the solids overnight at 45° C. in a vacuum oven to yield 98 mg of the title compound (47%): mass spectrum (ion spray) m/z=572.3 (M+H−HCl).

Provenance & Evidence