HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 5-Bromo-2-methanesulfonyl-1,3-dimethyl-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium hydroxy sulfite | HCID 23707502 | — |
| Reactant | 5-Bromo-1,3-dimethyl-2-(methylsulfanyl)benzene | HCID 68519501 | — |
| Product | 5-Bromo-2-methanesulfonyl-1,3-dimethyl-benzene | HCID 68515942 | 50% |
Reaction Steps
Dissolve 5-bromo-1,3-dimethyl-2-methylsulfanyl-benzene (555 mg, 2.42 mmol) in methanol (30 mL) and treat with oxone (6.0 g, 9.8 mmol). Stir the mixture at ambient temperature for 1 hour. Filter the suspension through silica gel and elute with CH2Cl2 (100 mL). Evaporate the filtrate to give 316 mg (50%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07585977B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-45eb8a536d4d4b6eb4f628bbc4618e08 |
| Source note | uspto-grants-2009_09 |