HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenyl chloroformate → 4-Nitrophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Reactant | Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate | HCID 18187546 | — |
| Product | 4-Nitrophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate | HCID 57838889 | — |
Reaction Steps
4-(nitro)phenyl chloroformate (5.0 g, 24.8 mmol) was added to a solution of tert-butyl 4-(prop-2-ynyl)piperidine-1-carboxylate (4.25 g, 19.0 mmol) according to general procedure 1. Yield=5.72 g, 80%. m/z MH+=289.04. HPLC rt=10.4 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589076B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-da9bd1bd873c4c3f9e9d3f80dd523fb3 |
| Source note | uspto-grants-2009_09 |