HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorophenyl chloroformate → 2-Chlorophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorophenyl chloroformate | HCID 4184068 | — |
| Reactant | Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate | HCID 18187546 | — |
| Product | 2-Chlorophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate | HCID 57838891 | — |
Reaction Steps
2-(chloro)phenyl chloroformate (5.00 g, 26.2 mmol) was added to a solution of tert-butyl 4-(prop-2-ynyl)piperidine-1-carboxylate (4.50 g, 20.2 mmol) according to general procedure 1. Yield=4.56 g, 82%. m/z MH+=278.13. HPLC rt=9.3 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589076B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-3efbe6e168944a7b8b4d85491786d624 |
| Source note | uspto-grants-2009_09 |