Phosphorus oxychloride → 4-Chloro-1-(2-phenylvinyl)-1H-pyrazolo[3,4-d]pyrimidine

Participants

Role	Name	HCID	Charge
Reactant	Phosphorus oxychloride	HCID 24813	—
Reactant	1-(2-Hydroxy-2-phenylethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one	HCID 136383529	—
Product	4-Chloro-1-(2-phenylvinyl)-1H-pyrazolo[3,4-d]pyrimidine	HCID 85961616	—

POCl3 (14 g, 91 mmol) was added to 10 (2.56 g, 10 mmol) and the mixture was refluxed for 12 h and then cooled to room temperature.