4,6-Dichloropyrimidine → HCID 66990867, compound

HRID 733036Notes

Reaction equation

HRID 733036 reaction equation
Cl[C:2]1[CH:7]=[C:6](Cl)[N:5]=[CH:4][N:3]=1.[CH3:9][NH:10][C:11]1[CH:12]=[C:13]([OH:17])[CH:14]=[CH:15][CH:16]=1>>[CH3:9][N:10]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([OH:17])[CH:12]=1)[C:2]1[CH:7]=[C:6]([N:10]([CH3:9])[C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([OH:17])[CH:12]=2)[N:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 709434,6-DichloropyrimidineHCID 108205133-(Methylamino)phenol

Product 1

HCID 66990867HCID 66990867, compoundYield 43%

Procedure

This compound was obtained (yield 43%) based on the method described in Production Example 2B using 4,6-dichloropyrimidine instead of the 4,6-dichloro-2-ethylpyrimidine, and using 3-methylaminophenol instead of the 3-aminophenol.

Workup

  1. customThis compound was obtained (yield 43%)

Sources & evidence

ORD record
ord-99f97db067b44e37950e8a8dcf7fae3c
Source dataset
uspto-grants-2009_09
Patent number
US07589105B2

Reaction notes

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