Npc164516 → 9-(8-Methyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)-9h-xanthene-3-carboxylic acid diethylamide

Participants

Reaction Steps

Following Procedure 7 and substituting tropinone for N-carbethoxynortropinone, compound 6a was converted to the title compound. MS m/z=403.2 (M+1); 1H NMR 300 MHz (CDCl3) δ 1.2 (br s, 6H), 1.9 (m, 2H), 2.5 (s, 3H), 2.8 (m, 2H), 3.1 (m, 2H), 3.3 (m, 2H), 3.4 (br s, 2H), 3.6 (m, 4H), 7.0-7.3 (m, 7H).

Provenance & Evidence