HuagongsheHuagongshe Chemistry Print Report · For research reference only
[3-(Benzyloxy)-4-methylphenyl]methanol → 3-(Benzyloxy)-4-methylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [3-(Benzyloxy)-4-methylphenyl]methanol | HCID 24721056 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(Benzyloxy)-4-methylbenzaldehyde | HCID 16101389 | 39.3% |
Reaction Steps
To a solution of (3-benzyloxy-4-methylphenyl)methanol (1.0 g) in dichloromethane (50 mL) was added manganese dioxide (2.5 g), and this mixture was stirred at room temperature for 2 days. The insoluble material was removed by filtration and this filtrate was concentrated under reduced pressure. This residue was purified by column chromatography on silica gel (eluent: n-hexane/ethyl acetate) to give the title compound (0.39 g)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829040B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-7c1381551b2a40929e4a30a33a7f9c71 |
| Source note | uspto-grants-2014_09 |