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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 733288Generated: October 26, 2026

2,2,3,3,3-Pentafluoropropanol → 2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonate

https://huagongshe.com/reaction/733288

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,3,3,3-PentafluoropropanolHCID 9872—
ReactantTrifluoromethanesulfonic anhydrideHCID 67749—
Product2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonateHCID 277601997%

Reaction Conditions

Temperature90 °C

Reaction Steps

A mixture of trifluoromethanesulfonic anhydride (40 mL, 0.24 mol) and 2,2,3,3,3-pentafluoropropanol (25 mL, 0.24 mol) was heated under argon at 90° C. overnight. Then, the crude mixture was distilled at atmospheric pressure to give the desired product as a colourless oil (97% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07589125B2
Source datasetuspto-grants-2009_09
ORD IDord-5c7fcfdc30414347a5f208e1333ccbe4
Source noteuspto-grants-2009_09