HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10151153, compound → HCID 10125869, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10151153 | HCID 10151153 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 10125869 | HCID 10125869 | — |
Reaction Steps
A solution of hydroxamic acid 3 (330 mg, 0.64 mmol) in 20 ml of methanol was hydrogenated under normal pressure with 70 mg of palladium on barium sulfate for about 5 hours. After filtration of the catalyst the solvent was evaporated and the crude product was purified by preparative HPLC to give a white solid. Yield: 133 mg (62%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589091B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-9176b54f9fdf43f3beeac5db957cf34f |
| Source note | uspto-grants-2009_09 |