HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-9H-xanthen-9-one → N,N-Diethyl-9-oxo-9H-xanthene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-9H-xanthen-9-one | HCID 231608 | — |
| Reactant | tert-Butyl 3-oxo-8-azabicyclo(3.2.1)octane-8-carboxylate | HCID 2794767 | — |
| Reactant | 3-(3-Bromo-xanthen-9-ylidene)-8-aza-bicyclo[3.2.1]octane | HCID 57839219 | — |
| Product | N,N-Diethyl-9-oxo-9H-xanthene-3-carboxamide | HCID 15953972 | — |
| Product | 3-(3-Bromo-xanthen-9-ylidene)-8-aza-bicyclo[3.2.1]octane | HCID 57839219 | — |
Reaction Steps
Using an adaptation of the method described in Procedure 7, substituting 3-bromo-xanthen-9-one, 3a, for 9-oxo-9H-xanthene-3-carboxylic acid diethylamide, 6a (13.69, 46 mmol) and 3-oxo-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester for N-carbethoxynortropinone, the title compound 3-(3-bromo-xanthen-9-ylidene)-8-aza-bicyclo[3.2.1]octane, 1b was obtained. MS m/z (MH+) 368.0/370.0
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589104B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-97bfd32f7ee942128f62c81346f703dd |
| Source note | uspto-grants-2009_09 |